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Phylogeography of Bacillus anthracis in the country of Georgia shows evidence of population structuring and is dissimilar to other regional genotypes

Khmaladze, Ekaterine and Birdsell, Dawn N. and Naumann, Amber A. and Hochhalter, Christian B. and Seymour, Meagan L. and Nottingham, Roxanne and Beckstrom-Sternberg, Stephen M. and Beckstrom-Sternberg, James and Nikolich, Mikeljon P. and Chanturia, Gvantsa and Zhgenti, Ekaterine and Zakalashvili, Mariam and Malania, Lile and Babuadze, Giorgi and Tsertsvadze, Nikoloz and Abazashvili, Natalia and Kekelidze, Merab and Tsanava, Shota and Imnadze, Paata and Ganz, Holly H. and Getz, Wayne M. and Pearson, Ofori and Gajer, Pawel and Eppinger, Mark and Ravel, Jacques and Wagner, David M. and Okinaka, Richard T. and Schupp, James M. and Keim, Paul and Pearson, Talima (2014) Phylogeography of Bacillus anthracis in the country of Georgia shows evidence of population structuring and is dissimilar to other regional genotypes. PLoS ONE, 9 (7). e102651. ISSN 1932-6203

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Publisher’s or external URL: http://dx.doi.org/10.1371/journal.pone.0102651


Sequence analyses and subtyping of Bacillus anthracis strains from Georgia reveal a single distinct lineage (Aust94) that is ecologically established. Phylogeographic analysis and comparisons to a global collection reveals a clade that is mostly restricted to Georgia. Within this clade, many groups are found around the country, however at least one subclade is only found in the eastern part. This pattern suggests that dispersal into and out of Georgia has been rare and despite historical dispersion within the country, for at least for one lineage, current spread is limited.

Item Type: Article
ID number or DOI: 10.1371/journal.pone.0102651
Keywords: Bacillus anthracis; bacterial ecology; Bacterial evolution; bacteria -- Population biology; Bacteriology; Biology and life sciences; Computational biology; diversity; Evolutionary Biology; Evolutionary systematics; Genetics; Genome evolution; Genome sequencing; Genomics; Medical microbiology; Microbial evolution; Microbial pathogens; Microbiology; Molecular biology; Molecular biology techniques; Organismal evolution; Phylogenetics; Phylogeography; Population genetics; Research Article; Sequencing techniques; strains
Subjects: Q Science > QR Microbiology
NAU Depositing Author Academic Status: Faculty/Staff
Department/Unit: Research Centers > Center for Microbial Genetics and Genomics
Date Deposited: 16 Oct 2015 17:59
URI: http://openknowledge.nau.edu/id/eprint/1715

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