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Molecular diversity of Bacillus anthracis in Italy

Fasanella, Antonio and Van Ert, Matthew and Altamura, Settimia A and Garofolo, Giuliano and Buonavoglia, Canio and Leori, Guido and Huynh, Lynn and Zanecki, Shaylan and Keim, Paul (2005) Molecular diversity of Bacillus anthracis in Italy. Journal of Clinical Microbiology, 43 (7). pp. 3398-3401. ISSN 1098-660X


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Publisher’s or external URL: http://dx.doi.org/10.1128/jcm.43.7.3398-3401.2005


We used multiple-locus variable-number tandem repeat analysis (MLVA) to type 64 Bacillus anthracis isolates from outbreaks that have occurred during the past 40 years in Italy. MLVA of the 64 isolates revealed 10 unique genotypes; 9 of these genotypes and the majority of isolates (63/64) belonged to the previously described genetic cluster A1.a. Within the A1.a isolates, two previously described genotypes (G1 and G3), which differ by a single mutation in the pX01 locus, account for the majority of isolates in the country (53/63). The low diversity of B. anthracis genotypes in Italy suggests a single, dominant historical introduction, followed by limited localized differentiation.

Item Type: Article
Publisher’s Statement: Copyright © 2005, American Society for Microbiology
ID number or DOI: 10.1128/JCM.43.7.3398-3401.2005
Keywords: Bacillus anthracis; Anthrax; Italy; genotype;
Subjects: Q Science > QR Microbiology > QR355 Virology
MeSH Subjects: B Organisms > B04 Viruses
Department/Unit: College of Engineering, Forestry, and Natural Science > Biological Sciences
Date Deposited: 15 Jan 2016 16:40
URI: http://openknowledge.nau.edu/id/eprint/834

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